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It is shown that the introduction of immune plasma significantly reduces mortality (from 16 to 1%) in an experiment on monkeys shows the effectiveness of ribavirin (virazole).


  • Prognosis: Mortality is usually between 3 and 15%.
  • Prevention of Ezetimibe hemorrhagic fever.

Specific prophylaxis has not been developed. Destruction of rodents living in houses. Argentine hemorrhagic fever (AHF) is a natural focal non-transmissible virosis endemic to a number of zetia of South America, occurring with the development of intoxication, hemorrhagic syndromes and multiple organ failure.

The disease was described in 1943 in the Argentinean province of Buenos Aires, later in other provinces of the country and a number of countries on the continent. The causative agent of the disease was isolated in 1958 by A.S. Parodi from a patient in a hospital in Junin (province of Buenos Aires). After the development of methods of immunoprophylaxis, the number of diseases has decreased markedly. The causative agent - Junin virus belongs to the antigenic complex of Tacaribe viruses of the New World of the Arenaviridae family.

Argentine hemorrhagic fever is a natural focal non-transmissible virus. The natural reservoir of Ezetimibe pills is the hamster rodents Calomys musculinus, C. laucha (family Cricetidae) and possibly other rodents.

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The centers of infection are located in rural areas of Argentina (the provinces of Buenos Aires, Santa Fe, Cordoba and La Pampa), where several hundred patients are registered annually. After introduction and primary replication of Junin virus in lymphoid tissue, it developsshort-term viremia and multiple organ dissemination of the pathogen. In the defeat of endothelial cells of microvessels and parenchymal organs, direct viral damage to cells and reactions of zetia and cellular immunity are of primary importance. The development of neutralizing antibodies ensures the elimination of the virus from the blood within 7-10 days.

The incubation period lasts from 6-8 to 13-16 days. The initial period of the disease usually develops gradually. In the first 3-4 days, subfebrile condition, headache, myalgia, irritability and sleep disturbance are noted.

A characteristic symptom of the disease is bradycardia. some patients develop oliguria. The appearance of signs of Ezetimibe pills is described. The development of symptoms of necrotizing hepatitis is possible. The period of convalescence proceeds with a lytic decrease in temperature and a slow recovery of the patient.